My nomination for the best science fiction and fantasy book of 2016 goes to "Murphy's Law of Vampires" by Declan Finn.
A fantastic mix of horror, fantasy, romance, and science fiction, the Love at First Bite series has been a lot of fun and one of the best newer series I'm currently reading.
The last time we've gotten a vampire series this fun Corey Haim was still with us. It also helps that Mr. Finn goes as old school as possible with his depiction of vampires. No sparkly nonsense or anything of the sort here.
As a sidenote: I'm currently halfway through the third book and will hopefully have a review up for it by the end of the month. Spoiler alert: it's what you would expect!